Senior Scientific Director - Scientific Lead Drug Delivery for bRo5 Molecules (m/f/d)
Location: Bayer Wuppertal, North Rhine-Westphalia, Germany
Overview
As we expand our druggable target space, we are seeking a highly motivated Scientific Lead for the internal development and external leveraging of innovative scientific advances aimed at overcoming the human intestinal barrier. This role focuses on safe chemical, enzymatic, or mechanical means to enhance oral drug absorption, particularly for drug molecules/modalities beyond the traditional Rule of 5 (bRo5). The successful candidate will play a crucial role in expanding the orally deliverable drug space through formulation technology and biorelevant in vitro and in vivo models, supporting both pre-clinical and clinical development of these new modalities.
Responsibilities
* Drive the strategy for the evolving field of drug delivery for bRo5 molecules (including peptides, degraders, and efflux substrates) in alignment with Bayer Pharma pipeline needs
* Serve as the scientific expert to evaluate novel oral delivery technologies for poorly permeable drugs, utilizing biorelevant in silico, in vitro, ex vivo, and in vivo models
* Leverage external scientific network to harness innovation that propels our pipeline forward through novel delivery methodologies as well as monitor competitor activities and ensure freedom to operate (FTO)
* Lead and co-create scientific expert communities across R&D for the effective delivery of bRo5 molecules
* Act as a scientific integrator and multiplier of internal capabilities across various Pharma R&D clusters to drive scientific excellence in drug delivery
* Collaborate closely with the internal Advanced Drug Delivery team to implement and develop pathways into clinical development
Qualifications
* Ph.D. in Pharmaceutical Sciences or a closely related field with long-term experience of professional experience in the industry, specifically in novel drug delivery technologies at the interface of Pharma research and development
* Proven scientific track record demonstrated by key publications, patents in the field, and presentations at scientific conferences
* Strong external network and in-depth knowledge of the relevant landscape, including universities, CROs, and CDMOs
* Solid understanding of Pharma R&D processes and strong acumen in Chemistry, Manufacturing, and Controls (CMC)
* Embody our VACC (Visionary, Architect, Catalyst, and Coach) leadership behaviors, showcasing high self-awareness and system awareness
* Excellent communication skills that facilitate effective collaboration, strategic end-to-end and global thinking, alongside proven organizational and planning abilities, and exceptional stakeholder management skills
* High energy and focus on vision; self-motivated with a strong sense of ownership and urgency
* Fluent in English written and verbal; proficiency in a second European language, especially German, would be an asset
Other details
The position is available for both full-time and part-time employment.
Why Bayer?
* We offer a competitive compensation package with base pay and annual bonus
* Flexible hybrid work models and part-time arrangements where possible
* Support for families including company daycare centers and childcare assistance
* Access to learning and development opportunities through Bayer Learning Academy, development dialogues, and coaching
* Health awareness and self-care opportunities through health checks and our health platform #machtfit
* An inclusive work environment that welcomes and supports you
Equal Opportunity
Bayer welcomes applications from all individuals, regardless of race, national origin, gender, age, physical characteristics, social origin, disability, union membership, religion, family status, pregnancy, sexual orientation, gender identity or any unlawful criterion under applicable law. We are committed to treating all applicants fairly and avoiding discrimination.
Location
Germany: North Rhine Westfalia: Wuppertal-Aprath || Germany: Berlin : Berlin
Division
Pharmaceuticals
Reference Code
849106
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