About
Madrigal is a biopharmaceutical company focused on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH), a serious liver disease with high unmet medical need. Left untreated, MASH can lead to progressive liver scarring, cirrhosis, liver failure, liver cancer, need for transplant and premature mortality. Our goal is to halt or reverse liver scarring (fibrosis) and resolve MASH before patients experience the devastating complications of cirrhosis.
Madrigal’s ambitious research program led to the first U.S. Food and Drug Administration (FDA)-approved treatment in MASH. This therapy is also now approved in Europe with approval expected in UK in 2026. Madrigal is in the process of establishing a dedicated UK team focused on delivering this groundbreaking therapy.
We focus on integrity, collaboration, and innovation while striving to improve patient outcomes. If you thrive in a results-driven, patient-centric culture, we invite you to be part of this journey.
Position Summary
The Madrigal MSL will build scientific partnerships with Healthcare Professionals and decision
makers using evidence-based science and non-promotional scientific exchange. The MSL will serve as a point of contact for the latest scientific and clinical information regarding Madrigal’s novel NASH research program to thought leaders, academic centers, community group practices and regional professional organizations. The MSL will report external insights to better understand MASH diagnosis and treatment landscape. Strategically support the development and utilization of disease state educational materials in the field as needed through disease education, scientific collaboration, clinical trial support, and scientific exchange.
Key Responsibilities
* Identify, develop and maintain relationships with leading influential experts, key thought Leaders (TLs) and health care professionals (HCPs) in fields of medicine or research relevant to the NAFLD/NASH.
* Build peer-to-peer relationships with TLs and HCPs.
* Identify and engage key TLs, HCPs, and investigators in proactive scientific exchange on disease landscape and reactive exchange on mode-of-action and clinical data.
* Represent the company at selected scientific congresses and professional society meetings.
* Deeply understand the fatty liver therapeutic area (NAFLD/NASH), key stakeholders, and healthcare landscape (i.e. reimbursement/access, diagnostic, testing) in your region.
* Help execution of medical plans by representing the medical expertise in NAFLD/NASH and Through scientific engagement with the medical community in Hepatology and Gastroenterology.
* Attend relevant scientific meetings and conferences and support development of summaries of key data, presentations, or symposia.
* Collaborate with other internal team members (i.e., commercial, payer/access, clinical development) to share regional insights/learnings and contribute to respective strategies.
* Assist in the scientific training for Commercial and other internal colleagues regarding products and the conditions they treat utilizing approved materials.
* Provide scientific expertise and support for speaker training and advisory boards as requested.
* Respond to external inquiries and deliver appropriate clinical and scientific information.
* Develop and deliver scientific training.
* Gather careful information from TLs/HCPs and report back to help develop clinical, as well as a commercial strategy.
* Operate in a highly ethical manner and comply with all laws, regulations and policies.
* Complete mandatory training in assigned timelines upon hire as well as when new policies, SOP’s guidance is issued.
* Adhere to internal standard processes and comply with regulatory and compliance requirements.
* Working knowledge of relevant research procedures as well as EMA and other ethical guidelines relevant to the pharmaceutical industry.
Qualifications
* 3+ years medical field experience (MSL or similar)
* Advanced degree in healthcare or science-related area of study (e.g., MD/DO, PharmD, PhD, DNP, PA-C) or other life sciences or equivalent with solid medical/technical background
* Hepatology / Gastroenterology and/or Fatty Liver experience is strongly preferred.
* Working knowledge of regulatory, health technology assessment, and disease management for NAFLD/NASH is strongly preferred.
* Ability to function well, both independently and within a team setting, in a dynamic, fast-paced environment. Team orientated and ability to work collaboratively towards common objectives.
* Ability to exhibit an entrepreneurial mindset and proactive approach, demonstrating ownership, adaptability to change, and effectiveness within a rapidly growing organizational environment.
* Ability to deeply understand and convey emergent scientific information
* Good interpersonal skills, including communication, presentation, persuasion, and influence.
* Proficiency with technology – computers, video conferencing, key software (e.g., Microsoft Office, CRM tools)
* Willing to travel internationally
* Fluent in English & German