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Director, analytical strategy

Berne
CSL
Director
Inserat online seit: 16 Juni
Beschreibung

The Analytical Strategy Director is a key scientific and strategic leadership role. In this position you will be responsible for developing and driving analytical strategies that support drug discovery, development, and regulatory approval. The position ensures the implementation of robust, compliant, and innovative analytical approaches across preclinical and clinical development programs, as well as throughout product life cycle management (LCM).

Main Responsibilities & Accountabilities

Strategic Leadership

* Develop and lead the global analytical strategy aligned with program and corporate goals
* Provide scientific and regulatory guidance for analytical plans across all development phases (discovery → post-marketing)
* Drive innovation in analytical technologies, platforms, and workflows
* Represent analytical function in cross-functional governance and decision-making forums


Scientific Oversight

* Oversee development, validation, and implementation of analytical methods (e.g., LC-MS/MS, ligand binding assays, biomarkers, immunogenicity)
* Ensure high-quality data generation for PK, PD, biomarker, and immunogenicity studies
* Review and approve analytical study designs, reports, and regulatory documentation
* Troubleshoot complex scientific and technical challenges


Regulatory & Compliance

* Ensure compliance with global regulatory guidelines (FDA, EMA, ICH, GLP, GCP)
* Lead analytical sections of regulatory submissions (IND, CTA, NDA, BLA, MAA)
* Interface with regulatory agencies and respond to health authority queries
* Maintain inspection readiness and quality standards


Cross-Functional Collaboration

* Partner with Clinical Pharmacology, DMPK, Toxicology, Biomarkers, and Clinical Operations
* Support translational strategy and dose selection decisions
* Manage external CROs, academic collaborators, and technology vendors


Leadership & Management

* Lead and mentor analytical scientists and project leaders
* Manage budgets, timelines, and resource allocation
* Build and scale analytical capabilities and infrastructure


Qualifications & Experience Requirements

* PhD in analytical Chemistry, Pharmaceutical Sciences, Biochemistry, or related field (or MSc with extensive experience)
* Typically 12–15+ years in bioanalysis within biotech, pharma, or CRO environments
* Deep expertise in LC-MS/MS, ligand binding assays, biomarkers, and immunogenicity testing
* Strong knowledge of regulatory requirements and analytical validation standards
* Proven leadership and strategic program experience
* Experience supporting regulatory submissions and health authority interactions

Are you interested? We are looking forward to receiving your online application.

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