The CRC/TRR 417 "Cellular Communication in the Stroma of Colorectal Cancer: From Pathophysiology to Clinical Translation”, focusing on understanding and therapeutically targeting the tumor microenvironment in colorectal cancer was granted to Goethe University Frankfurt, together with Friedrich-Alexander University Erlangen-Nürnberg and the University of Freiburg by the DFG earlier this year. This interdisciplinary research consortium aims to overcome resistance to immunotherapies by reprogramming stromal and immune cells and integrating insights from the gut microbiome. We are seeking 30 Doctoral Candidates (m/f/d) to join the TRR 417 on all three sites, pursuing functional cancer research on different aspects of cellular communication in the tumor microenvironment of colorectal cancer. The positions are integrated into the structured education program of the Integrated Research Training Group (IRTG) and provide ample networking opportunities amongst the doctoral candidates as well as with the more established researchers in the TRR 417. The IRTG sets out to educate tomorrow’s specialists in academic research, clinical practice and pharmaceutical industry that work towards improving the life quality and expectancy of CRC patients. 30 Doctoral Researcher Positions in Colorectal Cancer Research The participating laboratories cover a broad range of unique and complementing expertise. They offer a variaty of different projects ranging from the role of CAFs, vascular cells or the extracellular matrix, to soluble mediators and the microbiome to immune cells in colorectal cancer. Visit https://trr417.de to read more about the particular projects. Master’s degree in cell biology, life sciences or comparable areas. Strong interest in cancer research. High motivation, curiosity, proactivity and creativity. Willingness to engage in a collaborative environment. Proficiency in English. Outstanding structured training program in the field of colorectal tumor stroma. Excellent mentorship and development of a scientific profile. A vibrant international cancer research environment. A collaborative and friendly atmosphere. A salary in accordance with the agreement for public service (E13, 65%), including social benefits, available for 3 years with the option for extension.