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Senior manager biostatistics (m/f/d)

Bad Homburg
Fresenius Kabi
Senior Manager
Inserat online seit: 14 April
Beschreibung

Your responsibilities

1. Management, review and evaluation of biostatistical solutions and strategies for pre-clinical and clinical studies (phase 1-4, non-interventional incl. RWE studies) conducted and supported by Fresenius Kabi

2. Biostatistical assurance of quality control for Fresenius Kabi company sponsored trials worldwide, including guidance and oversight of contract research organizations to ensure project timelines and goals

3. Study planning, including study design discussions and sample size calculations

4. Development of statistical analysis plans (SAPs)

5. Conduct of statistical analyses and interpretation of statistical results

6. Contribution to clinical study reports, including integrated summaries for submissions

7. Participate in the development of CRFs, edit check specifications, and data validation plans

8. Contribute to the creation, maintenance, documentation, and validation of standards for programming tools, outputs, and macros

9. Statistical programming for Quality Control of critical outputs

Your profile

10. You have a completed university degree in (Bio-) statistics or mathematics or equivalent

11. You have at least 5 years experience in CROs and / or the pharmaceutical/biotechnology industry

12. You enjoy working on challenging scientific projects in an international setting and in multidisciplinary teams

13. You are passionate about clinical development and analysis, comprehensive knowledge of statistical methodology in design and analysis needed for clinical research

14. You are highly motivated to explore and implement AI‑supported methods for practical biostatistical applications and efficiency gains in clinical studies

15. You bring knowledge of Real-World research methodology

16. Experience in PK/PD studies (BE studies) / adaptive designs is a plus

17. Excellent knowledge of SAS is mandatory, knowledge of R programming is a plus

18. You have a solid understanding & implementation of CDISC requirements for regulatory submissions (in particular ADaM)

19. You have strong communication skills to present and explain the methodology and consequences of decisions

20. You are fluent in English (written & spoken)

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