From Oct 1st 2025 at the Department of Neuropathology at Heidelberg University Hospital.The Division of Molecular Neuropathology is seeking an ambitious bioinformatics expert with focus on DNA and RNA sequencing data analysis.As one of the largest neuro-oncology diagnostic institutions, we are centrally involved in clinical care for thousands of patients annually. We entertain a growing data collection, containing a wealth of data from multi-omics studies, histological imaging, and clinical research. This unparalleled resource provides the foundation for advancing diagnostics through data integration and workflow optimization.As a key member of our interdisciplinary team - including physicians, biologists, and computer scientists - you will shape the future of data-driven diagnostics. Your primary responsibility will be to iteratively enhance and supervise our next-generation- and third-generation- (Oxford Nanopore) sequencing data pipelines. You will design, implement, and optimize an analysis and interpretation infrastructure tailored for high-throughput data, supporting both clinical reporting and research efforts.Examples of our prior work in exploring novel methodologies for diagnostics include application of spatial sequencing (Ritter et al., Nat Cancer 2025) or intra-operative longread-sequencing (Patel et al., Nat Med In this environment with a variety of computational scientists, you can also interact with experts in other areas, including AI-based image analysis, proteomics, spatial and single cell-sequencing.Together, we aim to continuously translate cutting-edge molecular technology into the care delivery process, creating workflows that surpass traditional single-shot profiling. Your contributions will help integrate data science into every step of oncology care.Job-ID:V Field of application:NeuropathologieLocation:HeidelbergJob Category:ITWorking hours:full-time (38,5 Wochenstunden)Published: Limitation:PermanentContract:TV-UKYour tasksAs a key member of our interdisciplinary team, you will:Manage, enhance and supervise our NGS/ TGS data analysis workflowDevelop novel analysis tools at the forefront of sequencing technologiesTake responsibility for their seamless integration into patient careWork with data engineers to implement automated workflows for generating clinical reports and systematic downstream analyses in specialized web applicationsAdvance the digital transformation of brain tumor research and diagnosticsYour profileA degree in computer science, bioinformatics, or a related field. Applications on various entry levels are welcomeExperience working with NGS data pipelines, optimally including optimization and integration into complex workflowsStrong analytical and problem-solving skills, with a structured and results-oriented mindsetA collaborative spirit and the ability to thrive in an interdisciplinary environmentAwareness of the clinical relevance of the workWe offerGoal-oriented, individual training and development opportunities (e.g. use of AI applications in NGS/ TGS analysis)Working with the latest techniques / technical equipment for short- and long-read sequencingFlexible working hours within the framework of flexitimePossibility of doctoratePossibility of habilitationPossibility to publish scientifically is offered and supportedRegular team meetingsInterdisciplinary cooperationA vibrant academic setting in Heidelberg, one of Europe's top research hubsCollectively agreed remuneration (TV-UK E13), attractive company pension scheme (VBL)30 days vacationSustainable travel: job ticketFamily-friendly working environment: cooperative arrangements for childcare, subsidy for child vacation care, advice for employees with relatives in need of careWide range of health, prevention and sports offersContact & ApplicationFor further information please contact Dr. Stefan Hamelmann via e-mail.Interested?Applications will be accepted until via online.NeuropathologieProf. Dr. Dr. med. Felix Sahm – stv. Ärztlicher Direktor, NeuropathologieIm Neuenheimer Feld 22469120 HeidelbergNote: The UKHD is subject to the provisions of the Infektionsschutzgesetz. Therefore, a valid measles immunity certificate is required for all persons employed at the UKHD.The UKHD embraces diversity and values diversity.Regardless of age, gender, sexual identity, disability, origin or religion, we offer everyone the same opportunities. If one gender is underrepresented in a particular area, we place particular emphasis on counteracting this imbalance. If they have the same aptitude, qualifications and professional performance, we give priority to people with severe disabilities when considering them for vacancies.Classification is based on qualifications and personal requirements. The salary (gross) is for a full-time position and does not include the annual bonus or other allowances.