* you're in the middle of it
The Department of Hematology and Oncology at the Goethe University Hospital Frankfurt offers the full spectrum of blood and cancer diagnostics and therapy. The DFG Emmy-Noether research group of Dr. Sebastian Scheich is part of the Frankfurt Cancer Institute (FCI, ) and focuses on aggressive lymphoma biology and signaling. The lab is furthermore funded by grants from philantropy and several governmental organizations, is embedded in a vibrant research environment within the FCI and maintains lively international collaborations. We apply cutting-edge technologies including genome-wide CRISPR/Cas9 screens, quantitative functional proteomics and super resolution microscopy (dSTORM, single molecule tracking, SIM) to dissect oncogenic signaling pathways, study therapy resistance mechanisms and to find novel therapeutic vulnerabilities. We are looking for a highly motivated postdoctoral researcher to join our team.
The position is limited to three years.
Your Role
* Design, execute, and interpret genome-scale CRISPR/Cas9 screens and functional proteomic approaches, including comprehensive profiling of post-translational modifications
* Application and further development of basic and advanced molecular techniques, including advanced cloning, tissue culture, flow cytometry, and protein expression analysis
* Intellectual contribution to project direction, complex data analysis, interpretation, and dissemination of results
* High degree of scientific independence, including strategic experimental planning, execution, data analysis, and integration of multi-modal datasets within the field of lymphoma research
* your skills are what we're looking for
* The applicant is expected to hold a PhD in Biology, Biochemistry, Molecular Medicine or a related field
* Strong background and experience in molecular biology methods such as advanced cloning, mammalian tissue culture, flow cytometry and protein biochemistry
* Hands-on experience in conducting large functional genomic screens and/or proteomic experiments
* Experience in bioinformatics and data analysis of proteomic datasets or sequencings is considered advantageous
* Confidence and willingness to work with rodent models ideally with hands-on experience
* Very good communication skills in English
* Fascination and motivation for biomedical research in the field of cancer biology
* Ability to work in a team, sense of responsibility and proactivity
* Due to legal regulations, valid proof of measles immunity / measles vaccination is required
* you'll be offered a lot
* In addition to an attractive salary based on a collective agreement with an annual special payment, you benefit from long-term security through company pension scheme
* Funding secured for at least 3 years and extension possible if needed
* Internal and external training for your professional development
* Interaction with the National Cancer Institute (Bethesda, USA)
* Full access to FCI facilities
* Young and enthusiastic working environment in an international, multidisciplinary team
* Benefit from our attractive health offers. We offer regular online and face-to-face courses on nutrition, relaxation, sports and exercise
* Part-time employment is possible, we offer childcare in our daycare center (if you have any questions, please contact UKF-Familienservice), child care during holidays
* Free public transport in all Hessen (Free State Ticket Hessen)
* International and cosmopolitan region
* Uniklinik-Campus, Mensa, Cafés
* Insights: Instagram, YouTube, LinkedIn
* FAQ´s for new employees
It's time to join our team
Contact:
Dr. Sebastian Scheich
Phone:
Mail:
Application Deadline:
We welcome applications from candidates of all genders. Women are currently underrepresented in these positions at Universitätsmedizin Frankfurt. Therefore, applications from women are especially encouraged. Applicants with severe disabilities will be given preferential consideration in cases of equal personal and professional qualifications.