PTogether with university partners at seven renowned partner sites, we have established the German Cancer Consortium (DKTK). /p pFor the DKTK partner site in Dresden we are looking for July 2025 abr / PhD Student on the topic «Optimizing Brain Tumor Treatment with Radiotherapy: Defining Tumor Microenvironment and Normal Tissue Interactions"br / Reference number: 2025-0101 /p p Dresdenbr / Full-timebr / DKTK Dresden, Translational Radiation Oncology /p pThe group Translational Radiation Oncology represents the liaison between preclinical studies and the research within Clinical Radiation Oncology. The focus is on high-precision technologies, including particle therapy and biological-driven individualization of radiotherapy. /p pYour Tasksbr / To improve therapeutic options for brain cancer patients, this project aims to study the tumor microenvironment and surrounding normal tissue in preclinical models: defining clinical target volumes, understanding biological mechanisms, and identifying combined therapeutic approaches to enhance treatment efficacy and minimize side effects. /p pYou will: /p p image tumor and normal tissue alterations using preclinical imaging modalities (Optical Imaging systems, CT, MRI)br / perform mouse cranial proton and photon irradiations with state-of-the-art image-guided radiation therapybr / perform multiplex immunofluorescence stainingbr / apply and develop image analysis workflows for histological evaluationbr / perform spatial analysis at the cellular level in histological tissuesbr / work in an interdisciplinary team with strong expertise in translational research and collaborate with clinical scientists: Radiation Oncology, Pathology, Radiomics, Biostatistics and Mathematical modelling /p pYour Profile /p p Master / Diploma in biology, biotechnology, medical physics or related fieldsbr / Knowledge in tumor/cell biology desirablebr / Basic skills in mammalian cell culture, molecular biology, microscopy and histological techniques would be advantageousbr / Strong interest in translational studies on experimental tumors including readiness to perform in vivo experiments (FELASA B is a plus)br / Experience or willingness to learn image analysis software (e.g. Fiji ImageJ, ilastik, CellProfiler) as well as programming languages (e.g. R, Python)br / Strong commitment, motivation and discipline to work independently and efficientlybr / Strong team player with the ability to succeed in a dynamic international environmentbr / Proficiency in written and spoken English /p pWe Offerbr / Excellent framework conditions: state-of-the-art equipment and opportunities for international networking at the highest levelbr / Doctoral salary with the usual social benefitsbr / Flexible working hoursbr / Family-friendly working environmentbr / Unleash your full potential: targeted training and mentoring through the DKFZ International PhD Program and DKFZ Career Servicebr / Access to international research networksbr / 30 days of vacation per yearbr / Possibility of part-time workbr / Sustainable travel to work: subsidized Germany job ticketbr / Our Corporate Health Management Program offers a holistic approach to your well-beingbr / Contact:br / Antje Dietrichbr / Phone: +49 351 458 7406 /p pThe position is limited to 3 years with the possibility of prolongation.br / Are you interested?br / Then become part of the DKFZ and join us in contributing to a life without cancer! /p pApply nowbr / We are convinced that an innovative research and working environment thrives on the diversity of its employees. Therefore, we welcome applications from talented people, regardless of gender, cultural background, nationality, ethnicity, sexual identity, physical ability, religion and age. People with severe disabilities are given preference if they have the same aptitude. /p pNotice: We are subject to the regulations of the Infection Protection Act (IfSG). Therefore, all our employees must provide proof of immunity against measles. /p pShare this job! /p pDeutsches Krebsforschungszentrum | Im Neuenheimer Feld 280 | 69120 Heidelberg | a /a /p