What you can expect
The candidate will join the ARPA-H project LIVE which aims to bioprint an entire human liver for transplantation in the context of acute liver disease. The role of the candidate will be (i) to identify and to characterise GMP grade human induced Pluripotent Stem Cell line suitable for the project, (ii) to produce, to charactersie and to quality control liver cells at large quantity for the project. For that, they will develop new methods for to differentiation hiPSC lines using bioreactor. The resulting cell will be then used to bioprint artificial liver in vitro in collaboration without the international network of collaborators of the ARPA-H LIVE program.
1. Cell culture production (grow, characterise, differentiate human pluripotent stem cells)
2. Application of previously determined analytical procedures
3. Filling, operation and calibration/programming of the instruments to be used
4. Evaluation and interpretation of the analysis results with regard to plausibility and quality
5. Receipt, documentation and tracking of valuable samples
6. Review and qualitative evaluation of the sample
7. Technical elaboration of the experimental setup
8. Maintenance of laboratory equipment, if necessary organization of external service and repair measures.
9. Supervision of general laboratory operations and organization
10. Maintenance of the laboratory workplace, taking into account occupational health and safety and disposal guidelines
11. Ordering and stocking, e.g. of consumables, media and solutions
12. Performance of analytical procedures (application of previously determined analytical procedures,filling, operation and calibration/programming of the instruments to be used, evaluation and interpretation of the analysis results with regard to plausibility and quality)
What you bring along
13. Bachelor or equivalent in cell biology, bioengineering or regenerative medicine.
14. Experience in tissue culture especially with human Pluripotent Stem Cells.
15. Basic experience in flow cytometry, QPCR, and confocal imaging.
16. Experience in working independently while keeping a strong team spirit.
17. Strong self-motivation, organizational skills, and ability to lead and develop scientific projects.
18. Scientific curiosity, analytical thinking, and interest in contributing to projects.
19. Ability to work in a team of young scientists, to be flexible, and flourish in a fast-paced environment.
20. Strong communication and interpersonal skills, ability to work collaborate effectively with individuals of different backgrounds in a multidisciplinary team, team orientated with excellent organizational skills including project management and good record keeping important.
21. Fluent English
What we offer you
22. A varied job in a forward-looking research institute
23. Pay group E9b TVöD VKA-K. The classification is based on qualifications, the respective experience level is calculated on the basis of professional experience. The annual salary (gross) is stated for a full-time position without special or additional payments. The collective agreement can be found .
24. Additional benefits customary in the public sector (including annual special payment, company pension scheme (VBL), capital-forming benefits)
25. Flexible working hours
26. 30 vacation days per year (with a five-day week)
27. Various support offers to balance work and family life (childcare, cooperation with voiio)
28. Very good training and further education opportunities
29. Mobile citizens' office on site
30. Corporate benefits (travel, leisure, shopping, etc.), Charité Gympass, JobRad
31. Very easily accessible and attractive workplace at the Campus Virchow-Klinikum, Augustenburger Platz 1, 13353 Berlin