Join us in shaping the future at the intersection of life sciences and engineering. The structured Graduate School Life Science Engineering at TU Darmstadt is seeking excellent international PhD students to join the EU MSCA-COFUND program trainLSE. Following a successful first call, we are now opening the second call for applications and invite highly motivated and talented candidates to become part of our vibrant research community. PhD positions for In-Cell Structural Biology at the Technical University Darmstadt The project will investigate FKBP-Hsp90-steroid hormone receptor complexes by large-scale, site-specific, in-cell photo-crosslinking. The aim is to unravel key states and interactions partners of FKBP51, a key target for depression, obesity-induced diabetes and pain. Candidates are interested in biochemistry, molecular & chemical biology and the application to drug discovery and should have a master in life sciences or (bio)chemistry with a solid background in cell and molecular biology & protein biochemistry techniques, such as in Baischew_Engel et al., Nat Struct Mol Biol 2023, Geiger et al., Angew Chemie Int Ed. 2024, Taubert et al or Bulldan et al. We offer training in cutting-edge molecular biology techniques and dedicated mentoring in an interdisciplinary & international group, and industry exposure within the PROXIDRUGS and MC4DD consortia and the MoProX initiative. Further infos available here Please read the application requirements and selection process carefully BEFORE applying. Eligibility criteria Applicants must not be in the possession of a doctoral degree An excellent Master degree in life sciences or engineering disciplines, obtained no more than 5 years ago Applicants must not have been resident in Germany for more than 12 months in the last three years before application deadline (exceptions: compulsory military service, refugee status) ? Applicants finishing their Master’s after the deadline may still apply. In this case, upload your Bachelor’s certificate instead. Application requirements Applications must be submitted exclusively via the online form. Email submissions will not be considered. Required documents CV Motivation letter BSc and MSc certificates and transcripts at least two references (contact details) proof of English proficiency (certificate, university confirmationm or prior academic work in English) We strongly encourage applicants to submit their own research proposal️ Full-time employment contract form TUDa, co-funded by the EU until the end of the program in March 2029 International and structured PhD program Interdisciplinary supervision and research environment Extracurricular seminars and training for developing transferable skills Mobility grant for conducting research abroad