Master students: In-cell structural biology and biophysics
03.02., Wissenschaftliches Personal
The Cryoskeleton Lab ( at Helmholtz Munich is looking for Master students who are interested in using in situ cryo-electron tomography, including correlative cryo-focused ion beam milling sample preparation and image processing to explore the molecular architecture of actin systems within unperturbed cellular environments. We have many projects available.
We are looking for Master students who are interested in joining our lab for their Master thesis.
Your tasks:
- Have a keen interest in electron microscopy (EM), fluorescence microscopy and actin structure and function
- Have a keen interest in learning cryo-electron tomography (cryo-ET), correlative cryo-focused ion beam milling (cryo-FIB) sample preparation and image processing
- Study actin-based processes critical for health and disease using the cryo-ET workflow, from cell sample preparation and optimization to imaging and data analysis
- Use computational tools for in-cell structural analysis of actin assembly and force generation
Your profile:
- Excellent BSc in biology, physics, biochemistry, bioinformatics, or related field of science
- Knowledge/experience with EM or other structural biology techniques
- Ability to work in an interdisciplinary (combining structural, molecular, cellular and theoretical approaches) and international team of researchers
- Fluency in English
Desirable qualifications:
- Experience with cell culture
- Experience with cryo-EM/ET
- Experience with (cryo-)FIB/SEM sample preparation
- Experience with fluorescence microscopy
- Experience with scientific scripting languages (Python and Matlab)
The position is suitable for disabled persons. Disabled applicants will be given preference in case of generally equivalent suitability, aptitude and professional performance.
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