Technician (BTA/MTA) for the DKTK Research Project "ASTRON" in part-time (50%) Reference number: 2025-0190 * Mainz * Part time 19,75 h/week * DKTK partner site Frankfurt/Mainz - Department of Hematology and Medical Oncology at the University Medical Center Mainz “Research for a life without cancer" is our mission at the German Cancer Research Center. We investigate how cancer develops, identify cancer risk factors and look for new cancer prevention strategies. We develop new methods with which tumors can be diagnosed more precisely and cancer patients can be treated more successfully. Every contribution counts – whether in research, administration or infrastructure. This is what makes our daily work so meaningful and exciting. ----------------------------------- Together with university partners at seven renowned partner sites, we have established the German Cancer Consortium (DKTK). At the earliest date possible, we are seeking for the DKTK partner site Frankfurt/Mainz a At the DKTK partner site Frankfurt/Mainz (work location: Department of Hematology and Medical Oncology at the University Medical Center Mainz), an MTA/TA is sought for the DKTK research project ''ASTRON". The main task is to carry out experiments (in vitro and 3D bioprints) based on next-generation cellular interventions that can work synergistically with mRNA intervention. The candidate will separately develop interventions and test these in conjunction with mRNA patterns. Your Tasks The main activities include: * Cell culture (immune cells, tumor cell lines, but also tissue explants from fresh, healthy or cancer patients, microscopy analysis) * CAR/TCR-engineering T cells * mRNA interventions within the tumor microenvironment * DNA and mRNA preparation, PCR, Western Blotting * Functional testing (tumor cell targeting and killing by CAR/TCR-equipped T cells, analysis of T cell metabolic fitness etc.) * In vivo oncology/PDX models (mouse studies) * Maintenance of in vitro cell lines * Administration and documentation (assist with analysis of data, the preparation of research publications and reports, conduct literatuer searches, and also order lab supplies) * Assist in designing and planning research project-related experiments with the group leader * Performing laboratory-based research with the requirements of good laboratory practice using a range of techniques, including in immunology, cellular biology, biochemistry and lately in vivo mouse studies Your Profile * BTA, MTA or equivalent * Prior experience with cell culture and in molecular biology and biochemistry methods * Team spirit * Good German and English communication skills We Offer Excellent framework conditions: state-of-the-art equipment and opportunities for international networking at the highest level 30 days of vacation per year Flexible working hours Remuneration according to TV-L incl. occupational pension plan and capital-forming payments Possibility of part-time work Family-friendly working environment Sustainable travel to work: subsidized Germany job ticket Unleash your full potential: targeted offers for your personal development to further develop your talents Our Corporate Health Management Program offers a holistic approach to your well-being