Fixed term of 22 months | Full-time with 38,5 h | Salary Grade TV-L E13 | European Institute for Molecular Imaging
We are UKM. We have a clear social mission and, with our focus on healthcare, research, and teaching, we bear a unique responsibility.
To meet our high standards every day, we are looking forward to your scientific expertise in the Sánchez Lab at the European Institute for Molecular Imaging. Here, we are interested in how receptors sense the environment and respond generating selective responses – ideally with you on board!
We will focus on an undervalued receptor family: plexins. These receptors are involved in neuronal development, but also in shaping the cardiovascular, musculoskeletal systems and kidney. Further, plexins regulate immune responses and cancer becoming an attractive drug target.
The position is funded by an Emmy Noether DFG grant and aims to combine single-molecule localization methods and cell biology to decipher the stoichiometry and dynamics of plexin receptors in living cells, the role of ligand binding and ligand-independent mechanosensing.
The European Institute for Molecular Imaging (EIMI) is an interdisciplinary institute within the University of Münster developing imaging methods allowing to visualize molecular processes inside organisms, tissues and cells. With the help of imaging, we perform cutting-edge research in vascular, inflammatory, infectious, neurodegenerative diseases, and cancer. The EIMI is located in the Multiscale Imaging Center (MIC), which hosts research groups from our university combining a broad range of state-of-the-art imaging technologies for the investigation of biomedical questions.
RESPONSIBILITIES:
1. You will generate fusion construct of plexins receptors with fluorescent proteins or tags for advanced microscopy
2. You will perform live-cell imaging experiments and analyze data
3. You will collaborate with other members of the team in advance microscopy and super-resolution techniques
4. You will develop leadership skills and supervise students
REQUIREMENTS:
5. PhD degree in life sciences (completed no longer than 2 years ago)
6. Strong interest in single molecule localization microscopy methods
7. Experience in cell and molecular biology (expertise in cloning is highly desired)
8. We encourage applicants with a broad experimental-analytical interest, as the job holder will contribute both to the development of new methods and their application to investigate the organization and dynamics of plexin receptors in the context of cancer
9. Oral and written communication skills - English (required) and German (desired)
10. Ability to work effectively in an interdisciplinary team
We seek a highly motivated, ambitious, and talented young scientist to join an enthusiastic and collaborative team in an outstanding scientific environment. Proven experience in data acquisition and analysis of advance microscopy imaging techniques (e.g. confocal microscopy, TIRF, FRET, STORM, DNA-PAINT) is desired.
WE OFFER:
11. Career development in a multidisciplinary and committed research team - Mentorship, creative thinking, problem solving, and teamwork will be strongly promoted
12. Work-life balance: Münster is one of the cities with the best quality of life
13. Modern infrastructure, international and collaborative research environment
For inquiries, please contact: Dr. Maria Florencia Sánchez,
Apply now via our career portal until 18.06.2025.