Our collegial and friendly research group (Prof. Hashemolhosseini, Chair Prof. Wegner) is interested in molecular physiological and pathophysiological aspects of skeletal muscle biology; in particular also muscular dystrophies, myopathies, myasthenias and muscle tumors (rhabdomyosarcoma).
Recent papers:
The impact of canonical Wnt transcriptional repressors TLE3 and TLE4 on postsynaptic transcription at the neuromuscular junction.
Gessler L, Huraskin D, Eiber N, Hashemolhosseini S. Front Mol Neurosci. 2024 Mar 27;17:1360368. doi: 10.3389/fnmol.2024.1360368. eCollection 2024. PMID: 38600964
The YAP1/TAZ-TEAD transcriptional network regulates gene expression at neuromuscular junctions in skeletal muscle fibers.
Gessler L, Huraskin D, Jian Y, Eiber N, Hu Z, Prószyński TJ, Hashemolhosseini S. Nucleic Acids Res. 2024 Jan 25;52(2):600-624. doi: 10.1093/nar/gkad1124. PMID: 38048326
In Adult Skeletal Muscles, the Co-Receptors of Canonical Wnt Signaling, Lrp5 and Lrp6, Determine the Distribution and Size of Fiber Types, and Structure and Function of Neuromuscular Junctions.
Gessler L, Kurtek C, Merholz M, Jian Y, Hashemolhosseini S. Cells. 2022 Dec 8;11(24):3968. doi: 10.3390/cells11243968. PMID: 36552732 A broad spectrum of molecular and cell biological methods, transgenic mouse models and diagnostic analysis of patient material will be used. We are looking for motivated applicants from the field of biochemistry/biology/chemistry/molecular medicine for a PhD project. We offer a friendly and collegial working atmosphere and a flat hierarchy.
We also help candidates on their further career path after graduation.