PhD Student (gn*) Biology, Molecular/Experimental Medicine, Biochemistry or related
Fixed-term for 3 years | Part-time with 65% | Salary according to TV-L E 13 | Clinic for Vascular and Endovascular Surgery - Laboratory for Vascular Biology | Job ID: 11239
We are UKM. We have a clear social mission and, with our focus on healthcare, research, and teaching, we bear a unique responsibility.
To meet our high standards every day, we are looking forward to your scientific expertise in the Laboratory for Vascular Biology at the Clinic for Vascular and Endovascular Surgery - ideally with you on board
We are seeking a motivated PhD candidate to join our research team investigating the role of gut microbiota-derived metabolites in cellular signaling processes, with a particular focus on aortic pathologies and endothelial integrity.
PROJECT:
This project aims to uncover how microbiota-derived metabolites influence the endothelial barrier function and neutrophil transmigration, with an emphasis on their implications in aortic disease development and progression. A key component of the project will also explore general metabolite-mediated signaling in the aortic endothelium, aiming to identify novel molecular pathways involved in vascular inflammation and remodeling.
Your Tasks
Analysis of human aortic tissue specimens
Execution of in vitro experiments using primary human aortic endothelial cells
Investigation of molecular mechanisms regulating endothelial barrier function and immune cell transmigration
Collaborative work with core facilities for genomics and proteomics to generate and analyze large-scale datasets
Identification and characterization of novel microbiota-metabolite-driven signaling pathways relevant to aortic endothelial function
What we expect:
Commitment to work in a multidisciplinary setting
Motivated, independent, and collaborative way of working
Master's degree in biology, molecular/experimental medicine, biochemistry, or related
Strong interest in vascular biology, immunology, and/or microbiota research
Strong methodological background with experience in cell culture (static and flow conditions), microscopy and molecular biology techniques (Western Blot, (RT) qPCR, cloning etc.)
What we offer:
Motivated and supportive working group
Committed mentoring
Access to cutting-edge technologies and core facilities in genomics, proteomics, and bioinformatics
Research laboratory with state-of-the art equipment
Innovative technologies
Excellent possibilities for career development
Active participation in conferences
For inquiries, please contact: Dr. Thorsten Eierhoff, eierhoft@uni-muenster.de
Apply now via our career portal until 15.10.2025 including:
Motivation letter (1 Page)
CV
Relevant certificates
Reference letter (welcome)
BENEFITS
Exciting Projects
Professional Development and Training
Interdisciplinary Collaboration
Part of Research Innovation
Additional Benefits
Exciting Projects
Professional Development and Training
Interdisciplinary Collaboration
Part of Research Innovation
Additional Benefits
(*gn=gender neutral)
The University Hospital of Münster is one of the leading hospitals in Germany. Such a position cannot be achieved by size and medical successes alone. The individual commitment counts above all. We need your commitment so that even with little things we can achieve great things for our patients. There are many possibilities open for you so that you may develop with them.
Universitätsklinikum Münster
Albert-Schweitzer-Campus 1, Gebäude D5
48149 Münster
www.ukm.de