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Postdoc - blood-brain barrier model development (all genders) (full-time, temporary for 24 months)

Bodman-Ludwigshafen
AbbVie
Model
Inserat online seit: 13 Juni
Beschreibung

Stellenbeschreibung The job that makes possibilities real in patients' lives. And yours. The job that helps you get ahead in life. Moving mountains together. Welcome to AbbVie! As part of an international company with 48,000 employees worldwide and around 3,000 employees in Germany, you will have the opportunity of addressing some of tomorrows unmet medical needs in close collaboration with your colleagues. Are you passionate about improving global health care? Do you want to contribute to improving patients' quality of life through your expertise? In a challenging work environment that offers opportunities of developing and increasing your own skills? Youve come to the right place! Moving mountains together – as PostDoc - Blood-Brain Barrier Model Development (all genders) (full-time, temporary for 24 months) AbbVie invites applications for a postdoctoral research position focused on advancing our understanding of drug transport across the blood-brain barrier (BBB). This role is pivotal in enhancing drug delivery for neurological and neuro-oncological therapeutics, addressing the significant challenge of drug penetration into the brain tissue. The successful candidate will engage in developing state-of-the-art in vitro models using human induced pluripotent stem cell (hiPSC)-derived cell types in transwell, organoid, and microfluidic systems. Responsibilities Develop and characterize advanced in vitro models of the BBB to serve as screening platforms for brain disposition of various drug modalities. Correlate drug absorption data using these models with human in vivo exposure data and integrate findings into pharmacokinetic models. Interact with stakeholders to adapt models according to project needs. Attend conferences to stay at the forefront of scientific innovation and engage with leading experts in the field. Design and write scientific papers

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