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Senior / principal scientist pharmacometrics

Ingelheim am Rhein
Boehringer Ingelheim
Scientist
Inserat online seit: 16 Oktober
Beschreibung

The Position Are you passionate about applying your pharmacometric skills, strategic thinking, and practical experience in data analysis? Would you like to join cross-functional clinical development teams, and do you feel like expanding your influence and deepening your knowledge in pharmacometric approaches? The Senior/ Principal Scientist - Pharmacometrics will independently perform high quality pharmacometric (PMx) analyses on an asset and study level essential for internal decision making and successful approval. The incumbent will represent Clinical Pharmacology/PMx in (pre-)clinical development teams, develop PMx strategies and author PMx documents. The position follows a hybrid working model with regular on-site presence. This position can be filled either as Senior Scientist or Principal Scientist in Ingelheim or Biberach. Tasks & responsibilities As Senior Scientist, you will develop the pharmacometric strategy and identify opportunities where pharmacometric approaches can further the understanding of pharmacological activity, efficacy and safety of a drug. Furthermore, you will join cross-functional teams as the PMx lead, where you work in close alignment with other team members and are responsible for the PMx data and data analysis strategy and advising (early) clinical development teams on opportunities and limitations of MIDD approaches. You will be responsible for the planning and execution of relevant pharmacometric analyses to support internal decision making, disease understanding and successful approval. Moreover, you will ensure the timely delivery of analysis-related documentation (e.g., dataset specification, analysis plans, and reports) and documents where you are co-author (e.g., asset evidence plan, pediatric investigational plan, submission documents). You will organize and manage projects with external organizations such as CROs or academic institutions. In addition, you will represent Clinical Pharmacology/PMx in internal initiatives and working/focus groups collaborating closely with other disciplines. Additional tasks for the Principal Scientist role: As Principal Scientist, you act with a higher level of independence and will provide consultancy and advice for other scientists and stakeholders as an internally and externally recognized scientist. You will also represent Clinical Pharmacology/PMx in internal and external initiatives/working groups such as focus groups in your area of expertise, across department initiatives, process harmonization, IMI calls, ISoP groups. Requirements PhD, MD or masteru2019s degree from an accredited institution in Pharmacometrics, Clinical Pharmacology, Pharmacy, Medicine, Mathematics, Biology, Statistics or relevant area of focus First experience in Pharmacometrics in the pharmaceutical industry, regulatory agencies, or academia Solid knowledge in applying PMx software (e.g., NONMEM, Monolix, R, PBPK software) and approaches (e.g., population pharmacokinetics, pharmacokinetics/pharmacodynamics, exposure response, disease progression modeling, model-based meta-analysis as well as PBPK) Basic knowledge in other data science fields, clinical pharmacology, clinical drug development, MID3, and regulatory guidelines. Additional knowledge in oncology, toxicology and DMPK, quantitative systems pharmacology, as well as applications of AI/ML in pharmacometrics/clinical pharmacology will be a plus. Strong team player, who is able to successfully act in the global context and with the ability to pro-actively identify issues and solutions Good interpersonal skills with the ability to interact effectively with people, internally and externally Additional requirements for the Principal Scientist role: Multi-years of relevant experience in Pharmacometrics in the pharmaceutical industry, CROs, regulatory agencies, or academia Several years of relevant experience in working in (pre-)clinical development teams Broad knowledge in applying PMx software and approaches Broad knowledge in other data science fields, clinical pharmacology, clinical drug development, MID3, and regulatory guidelines. Additional knowledge in oncology, toxicology and DMPK, quantitative systems pharmacology, as well as applications of AI/ML in pharmacometrics/clinical pharmacology will be a plus. Ready to contact us? If you have any questions about the job posting or process - please contact our HR Direct Team, Tel: 49 (0) 6132 77-3330 or via mail: hr.de@boehringer-ingelheim.com Recruitment process: Step 1: Online application - The job posting is presumably online until November 2nd, 2025. We reserve the right to take the posting offline beforehand. Applications up to October 27th, 2025 are guaranteed to be considered. Step 2: Virtual meeting in the period from beginning till mid of November Step 3: On-site interviews end of November All qualified applicants will receive consideration for employment without regard to a personu2019s actual or perceived race, including natural hairstyles, hair texture and protective hairstyles; color; creed; religion; national origin; age; ancestry; citizenship status, marital status; gender, gender identity or expression; sexual orientation, mental, physical or intellectual disability, veteran status; pregnancy, childbirth or related medical condition; genetic information (including the refusal to submit to genetic testing) or any other class or characteristic protected by applicable law.

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Home > Stellenangebote > Wissenschaft Jobs > Scientist Jobs > Scientist Jobs im Kreis Mainz-Bingen > Senior / Principal Scientist Pharmacometrics

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