Scientist Position: Unraveling Stromal-Epithelial Crosstalk in Colorectal Cancer
The University of Luxembourg is an international research university with a distinctly multilingual and interdisciplinary character.
We are seeking a highly motivated scientist to join our collaborative group investigating stromal-epithelial crosstalk in colorectal cancer initiation, progression, and therapy resistance. Our team uses cutting-edge single-cell RNA sequencing (scRNAseq) and spatial transcriptomics on CRC patient samples to identify novel epithelial cell states and distinct cancer-associated fibroblast subpopulations.
Key Responsibilities:
* Define how fibroblasts from healthy colon tissue transition into distinct CAF subtypes.
* Regulate epithelial plasticity and immune responses, promoting tumor progression and therapy resistance.
Requirements:
* PhD in Biological Sciences, Data Science, Computational Biology, or a related discipline.
* Strong computational background, proficiency in R and at least one additional scripting language.
* Solid knowledge of biostatistics and experience with single-cell sequencing data.
* Good understanding of cancer biology, immunology, cell biology, and molecular biology.
What We Offer:
* Collaborative, interdisciplinary environment.
* Contribution to the TARGET-SEC project's overarching goal.
* Modern institution with a personal atmosphere.
* Staff coming from 90 countries.
* Member of the 'University of the Greater Region' (UniGR).