About This Research Role
We are seeking a highly motivated PhD student to develop and apply computational multiscale models to investigate brain energy metabolism and its relation to neurodegenerative diseases like Parkinson's disease and Alzheimer disease.
The successful candidate will extend and embed an agent-based physiological 3D model of mitochondria into a continuous description of single-cell models for neurons and glial cells. The goal of this hybrid continuum/agent-based model is to investigate through a quantitative mechanistic model how mitochondrial morphology affects energetic states and can integrate mechanistically experimental findings of neurodegenerative disease research.
About the Ideal Candidate
* A Master's in engineering, computer science, mathematics, physics, biophysics, bioengineering or a related discipline
* Enthusiasm for interdisciplinary research, critical thinking and self-driven attitude
* Fascination with multiscale organisation of biological systems and the complexity of the brain
* Experience in spatiotemporal dynamics and corresponding simulations (including high-performance computing) is an asset
We Offer
1. A diverse, multilingual and international environment. A modern institution with a personal atmosphere and staff from 90 countries. Member of the