Accountability Cluster
Major Activities / Tasks
Accurate Execution of mRNA Production Processes
* Perform IVT reactions
* enzymatic processing
* purification
Reliable Performance of Analytical Methods
* Conduct standard analytical tests to monitor process performance
* UV spectroscopy,
* gel electrophoresis,
* RNA quantification,
* purity assessments
Maintenance of Laboratory Equipment and Work Areas
* Operate, clean, and calibrate assigned instruments;
* ensure workspaces remain organized and compliant with safety standards
Accurate Documentation and Data Recording
* Perform analysis of in-licensed manufacturing process and identify optimization/improvement potential keeping process robustness in mind
* Adapt in-licensed manufacturing processes and controls according to Cipla’s requirements harmonized with clinical development timelines including DNA process
* Build plans for execution of implementation of improvements into in-licensed original process
* Implementation of improvements in alignment with VP and CDO (mRNA)
* Continuous improvement of CMC processes and analytics
Support for Process Optimization and Scale-Up
* Assist scientists in
* executing experiments,
* collecting samples
* compiling results for process improvement studies
Educational qualifications:
* Completed vocational training as a Biological or Medical Technical Assistant (BTA or MTA)
* Alternatively, a Bachelor's or Master's degree in biotechnology, biology, or a related life sciences discipline
Relevant experience:
* 5+ years of experience in process development or relevant field
* Hands-on experience with IVT, enzymatic reactions, and purification processes including tangential flow filtration (TFF).
* Familiarity with molecular biology tools, mRNA handling best practices, and aseptic techniques.
* Strong organizational skills, attention to detail, and the ability to work both independently and in a team.
* Ability to document and communicate effectively in English; German language skills are a plus.