Research Associate for the Project “CryoCLEM sample transfer solutions to enable sustainable use of cryo-microscopes” as CryoCLEM Research Specialist § 28 Subsection 3 HmbHG
InstitutionFaculty of Mathematics, Informatics and Natural Sciences, Department of Chemistry, Technology Platform Light Microscopy
Salary level
Start date01.03.2026, fixed until 31.01.2029 (This is a fixed-term contract in accordance with Section 2 of the academic fixed-term labor contract act [Wissenschaftszeitvertragsgesetz, WissZeitVG]).
Application deadline16.01.2026
Scope of workfull-time position suitable for part-time
Your responsibilities
Duties include academic services in the project named above. Research associates may also pursue independent research and further academic qualifications.
Correlative light and electron cryo-microscopy (cryoCLEM) opens new avenues in structural biology by enabling resolving protein structures in situ within cells. To this end, cryoCLEM combines the advantages of light microscopy and cryoEM. Light microscopy allows for the identification and localization of cellular components using specific labelling with fluorescent dyes, while cryoEM provides superior resolution down to the sub-molecular scale. Recent years have seen significant improvements in the available cryoEM and light cryo-microscopy technologies, resulting in the rapid introduction of new instruments by manufacturers. In a project funded by the DFG, we will develop a modular, open-platform sample transfer station to streamline the movement of cryo-samples between different sample holders along a cryoCLEM workflow.
We are looking for a motivated researcher who will be in charge of developing and overseeing the testing of the novel cryoCLEM sample transfer station.
The position will be embedded in the Technology Platform Light Microscopy (TPLM) at University of Hamburg (). TPLM consists of several light microscopy facilities, including the Advanced Light and Fluorescence Microscopy (ALFM) facility at the Center for Structural Systems Biology (CSSB) Hamburg (). The ALFM facility has experience in developing tools for cryoCLEM workflows and closely collaborates with the cryoEM facility at CSSB.
The recruited candidate will be supported by the ALFM facility team during the whole project. Furthermore, the cryoEM facility team and CSSB researchers will provide feedback to achieve a well-usable design of the open-platform cryoCLEM sample transfer station. The recruited candidate will also be responsible for documenting and publishing the designs and testing results of the open-platform cryoCLEM sample transfer station, as well as supporting researchers in using the transfer station.
Your profile
A university degree in a relevant field, plus doctorate.
1. thorough understanding of the principles of correlative light and electron cryo-microscopy (cryoCLEM) and its application for biological research
2. profound expertise and experience in developing and implementing novel research methods
3. knowledge and experience in designing and building tools or components for light or electron microscopy, preferably for cryo-microscopy
4. experience with using CAD design software (e.g. Autodesk Inventor, SolidWorks)
5. experience in working with light-cryo-microscopes or cryoEMs is an advantage
6. proficiency in English (spoken and written, B2 or better)
7. initiative, planning and organizational skills
8. very good communication, ability to work in a team and resilience
We offer
9. Reliable remuneration based on wage agreements
10. Continuing education opportunities
11. University pensions
12. Attractive location
13. Flexible working hours
14. Work-life balance opportunities
15. Health management, EGYM Wellpass
16. Educational leave
17. 30 days of vacation per annum
Universität Hamburg—University of Excellence is one of the strongest research educational institutions in Germany. Our work in research, teaching, educational and knowledge exchange activities is fostering the next generation of responsible global citizens ready to tackle the global challenges facing us. Our guiding principle “Innovating and Cooperating for a Sustainable Future in a digital age” drives collaboration with academic and nonacademic partner institutions in the Hamburg Metropolitan Region and around the world. We would like to invite you to be part of our community to work with us in creating sustainable and digital change for a dynamic and pluralist society.
The University of Hamburg is committed to equity. Diversity enriches our university life, whether in our studies, research, teaching, education, or workplace. We therefore welcome all applications, regardless of gender, gender identity, sexual orientation, ethnic or social background, age, religion or belief, disability, or chronic illness.
Severely disabled and disabled applicants with the same status will receive preference over equally qualified non-disabled applicants.