About us
Our team conducts fundamental and translational research in the field of Systems Biology and Biomedicine. We focus on neurodegenerative processes, especially Alzheimer's and Parkinson's disease.
We are a young, dynamic, and international team, led by Prof. Carole Linster. A main objective is to unravel how metabolic impairments are involved in rare and more common neurodegenerative or neurometabolic diseases.
Key tasks include:
* Molecular biology techniques, including cloning, (q)PCR, vector design and production
* Preparation of DNA samples for sequencing and analysis of sequencing results
* Metabolite and RNA extraction, and sample preparation for metabolomics and transcriptomics analyses
* Set up and performance of various biochemical assays and protein purifications
* Mammalian cell culture and differentiation
* Cell transfection for gene silencing/overexpression
* Immunohistochemical/immunofluorescent staining
* Assist with microscopy and image analysis
* Assist with laboratory animal experiments
* Perform analysis of all generated experimental data, including statistics
* Make up and maintain stock/working chemical solutions, growth media, bacterial glycerol stocks, mammalian cell banks
* Contribute to the maintenance of various equipment pieces including FPLC protein purifier, UHPLC, fridges/freezers, pH-meter
* Maintain a clean laboratory setting and refill general consumable stocks
* Order, gather, inventory, and stock supplies for laboratory use
* Keep a record of current projects in a well-organized lab notebook
* Work in a collaborative environment, also with different service-based core platforms
* Contributing to methodology sections and figure generation for manuscripts submitted for publication in high-quality journals
* Presentation of research findings during internal scientific meetings
A Bachelor's or Master's degree in biochemistry, molecular biology, biotechnology, or another similar life science-related discipline. Prior experience with microbial and mammalian cell culture, molecular biology techniques, biochemical assays, protein purification, and HPLC will be considered as important assets. Excellent organizational skills and solid computer skills will be required. Good communication skills and English writing and speaking skills will be essential. Strong motivation to contribute specific parts to larger projects, to work in a team, and to support high-level, internationally competitive research will be indispensable.
Our institution offers modern equipment, a personal atmosphere, and a unique urban site with excellent infrastructure. Staff come from 90 countries. We are a member of the “University of the Greater Region” (UniGR). We have close ties to the business world and to the Luxembourg labour market. We partner with European institutions, innovative companies, and numerous non-academic partners.