We are looking for support in our Tumor Biology and Vaccines unit to start as soon as possible. The successful candidate will work with preclinical mouse tumor models to develop innovative cancer immunotherapies based on understanding and exploiting of cancer and immune cells metabolism. Our research interests include the characterization of tumor-infiltrating immune cell as well as metabolic manipulation of the tumor microenvironment during therapy, involving cancer mRNA vaccines and other cancer therapies. Our multidisciplinary team is responsible for a large variety of different projects within TRON and with external collaborators. Methodologically, we primarily focus on mouse cancer models and the immune cells within the tumor microenvironment, with additional in vitro analysis via Seahorse, flow cytometry and preparation of cell suspension for metabolic analysis. Exploring and improving state of the art and innovative immunotherapies in the field of cancer immunotherapy (e.g. RNA lipoplex-based vaccination, metabolic reprogramming of T cells & immune checkpoint inhibitors, adoptive cell transfer) following metabolic & immunogenic analysis. Planning, execution and analysis of preclinical mouse experiments including documentation according to official & internal guidelines. Processing of mouse tissues for in vitro analysis. Writing of standard operating procedures (SOPs). Pro-active contribution to tasks of general lab organization. A completed university degree (bachelor’s or master’s degree) in life sciences or related fields or apprenticeship as technical assistant FELASA function A (former FELASA category B) or similar qualification. Practical experience in conducting animal experiments is a must, including the capability of performing standard techniques (e.g. drug administration - i.v., i.p. s.c.; blood collection) Experience in cell culture and in vitro assays is desirable Basic knowledge in conduction metabolic assays would be a plus An understanding of basic immunology, ideally combined with knowledge of cancer immunotherapy and vaccinology would be a plus Oral and written communication skills in German and English. Ability to work independently and in synergy with working routines in a large and international team. Well-structured and organized working methods and excellent time management Enthusiasm and curiosity for the diverse activities of our research institute as well as the ability to work in a team completes your profile. A dynamic, innovative and creative research environment An open, collegial and cordial working atmosphere in a respectful corporate culture A high degree of diversity in the workforce Flat hierarchies Performance-related remuneration and other benefits The opportunity for personalised further training Job ticket (Deutschlandticket) incl. employer allowance Bike leasing (Businessbike) The opportunity for hybrid working