Master Thesis in Experimental Ophthalmology - Investigation of altered immune reactivities in glaucoma patients Our research team in the Experimental and Translational Ophthalmology Department at the University Medical Center of the Johannes Gutenberg University Mainz has extensive experience in basic and clinical research in the field of Ophthalmology. We are interested in understanding the underlying mechanisms leading to retinal and ocular surface diseases, such as Dry Eye Disease, AMD and Glaucoma. Evaluation of longitudinal disease markers can greatly contribute to a better understanding of disease progression. Furthermore, a detailed analysis of subgroups will further improve our understanding of glaucoma. Our laboratory is equipped with state-of-the-art proteomics and antigen/antibody microarray technologies, as well as comprehensive cell culture and biochemical assay facilities. We are now looking for motivated students to join our international team and support our research efforts. The project aims to investigate altered immune reactions in serum and tear fluid of glaucoma patients. The aim of these examinations is to diagnose/assess the risk of the disease as early as possible, as well as to be able to distinguish between the different forms of glaucoma. Investigation of subgroups of glaucoma in tear fluid and blood samples Identification and evaluation of markers for disease severity Further development of our lateral flow assay/rapid test for the evaluation of glaucoma disease based on the marker patterns in the tear fluid conduction Participation in general management of the lab Bachelor´s degree in Life Sciences successfully completed Proficient in English Self-motivated, detail-oriented, and able to work both independently and within a team Laboratory experience and strong interest in basic research and data analysis Comprehensive training and supervision An international team of dedicated scientists Access to state-of-the-art facilities for cell culture, metabolic analysis, proteomics, and immunoblotting The opportunity to continue to a PhD once the MSc has been successfully completed.