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Postdoc (f/m/d) on generative ai for de novo protein design

Dresden
Helmholtz-Zentrum Dresden-Rossendorf (HZDR)
Designer
Inserat online seit: 27 Januar
Beschreibung

With cutting-edge research in the fields of ENERGY, HEALTH and MATTER, around 1,500 employees from more than 70 nations at Helmholtz-Zentrum Dresden-Rossendorf (HZDR) are committed to mastering the great challenges facing society today.

The Center for Advanced Systems Understanding (CASUS) is a German-Polish research center for data-intensive digital systems research.

The Department of Machine Learning for Infection and Disease is looking for a
Postdoc (f/m/d) on Generative AI for de Novo Protein Design.
Your tasks

* Design of generative AI models (e.g., VAEs, GANs, Diffusion Models) to create novel protein sequences, fold structures, and functional molecules
* Engage with our international collaborators (Berlin, Dresden, London, Zurich, Taipei etc.) to understand existing approaches and datasets of natural and designed proteins
* Collaborate in the research team on other questions of machine learning, functional genomics, and genome instability
* Supervise junior lab members
* Present results at scientific meetings and publish high-impact peer-reviewed research

Your profile

* Completed university studies (PhD) in a relevant field, such as molecular biology, computational biology, bioinformatics, genetics, computer science, mathematics, or equivalent scientific background
* A solid background and motivation to learn more about structural/molecular biology, protein biophysics, generative models, software engineering, or a related subject
* Previous experience or interest in Generative Modelling, Protein Folding/Design, and Structural Biology is a plus
* Experience with AlphaFold, RFdiffusion, and RFdiffusion2 is a significant plus
* Strong motivation to work in a collaborative multidisciplinary environment
* Excellent programming skills in languages such as Python, C/C++ and CUDA
* Familiarity with modern deep learning frameworks like Tensorflow 2.x.x, PyTorch
* Mandatory experience with High-Performance Computing (HPC) cluster environments and the Slurm cluster environment is required
* Communication skills in English and in a professional context (presentation of research results at scientific meetings, colloquial discussions, writing of manuscripts)

Our offer

* A vibrant research community in an open, diverse and international work environment
* Scientific excellence and extensive professional networking opportunities
* Salary and social benefits in accordance with the collective agreement for the public sector (TVöD-Bund) including 30 days of paid holiday leave, company pension scheme (VBL)
* We support a good work-life balance with the possibility of part-time employment, mobile working and flexible working hours
* Numerous company health management offerings
* Employee discounts with well-known providers via the platform Corporate Benefits
* An employer subsidy for the "Deutschland-Ticket Jobticket"

We look forward to receiving your application documents (including cover letter, CV, diplomas/transcripts, etc.), which you can submit via our online-application-system.

Apply here
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