Rentschler Biopharma is a leading global contract development and manufacturing organization (CDMO) for biopharmaceuticals. From our headquarters in Laupheim, Germany, and our site in Milford, MA, USA, we offer end-to-end solutions, including bioprocess development and manufacturing, as well as related consulting activities such as project management and regulatory support. In Stevenage, UK, we have launched Rentschler ATMP Ltd. dedicated to cell and gene therapies.
We are a family-owned company with approximately 1.400 employees from 25 nationalities. What unites us at Rentschler Biopharma, is the passion for what we do. We empower our clients to help patients with serious or rare diseases. With our dedication and expertise, we convert medical research into outstanding biopharmaceuticals. Thus, we provide an important contribution to the global availability of essential therapies. Going forward, we are expanding our team to ensure our long-term sustainable growth. Join us and be part of a unique journey, shaping the future of biopharmaceutical manufacturing together!
Master Thesis in Process Science USP: High Cell Density Intermediates and N-1 Perfusion (m/w/d)
Topical background and tasks
The development of high cell density (HCD) process intermediates, to significantly shorten and de-risk the cell expansion, and N-1 perfusion enabled intensified fed-batch processes with an immense potential for streamlining and optimizing biomanufacturing processes. This thesis aims to investigate the implementation of HCD process intermediates and N-1 perfusion strategies to establish an intensified fed-batch processes for the production of therapeutic proteins.
* Development of robust HCD process intermediates
* Integration of N-1 perfusion-based cell banking
* Implementation of intensified fed-batch processes
* Optimization of process parameters
* Evaluation of process impact
This is important to us
* Degree in biotechnology, technical biology, bioengineering, biochemistry, chemistry, biology, biosciences or similar
* Experience in working with cell culture
* Knowledge of and interest in fed-batch and perfusion processes desirable
* Quick comprehension, analytical and solution-oriented thinking
* Independent and structured way of working and team spirit
* Confident handling of MS Office (Word, Excel, PowerPoint, Outlook, SharePoint)
* Combination of internship plus thesis with a total of 6-9 months
* Entry possible from July 24
What you can look forward to
* Collaborative work environment in a future-proof industry
* Attractive compensation
* Flexible working hours
* Occupational health management
* Exciting career opportunities
* An in-house company restaurant
Standort
Rentschler Biopharma, Laupheim