Medical Director (Global Clinical Development) (m/f/d)&##128205; Full-time, permanent
Pentixapharm AG is a research-driven radiopharmaceutical and precision oncology company focused on developing innovative theranostic therapies. We operate in a lean, science-driven biotech environment with a strong focus on execution and accountability.
We are looking for an experienced Medical Director (Global Clinical Development) to lead the overall medical and clinical strategy for our late-stage development programs, with a strong focus on diagnostic imaging and radiopharmaceutical development.
This role combines strategic leadership with hands-on execution across pivotal clinical trials, regulatory interactions, and benefit–risk assessment in a highly matrixed biotech environment.
Lead overall medical and clinical strategy for late-stage (Phase 2/3 and Phase 3 pivotal) development programs
Provide medical leadership for clinical trial design and execution, including diagnostic and therapeutic radiopharmaceutical studies
Author and review clinical protocols, Clinical IND sections, SAP-relevant sections, and Clinical Study Reports (CSRs)
Oversee benefit–risk assessment and interpretation of diagnostic and imaging performance data
Collaborate closely with Regulatory Affairs, Clinical Operations, Biostatistics, Translational Research, and external partners
Provide medical input to development strategy, endpoints, and go/no-go decisions
MD (or equivalent medical degree); Proven experience leading late-stage oncology or diagnostic development programs
Ability to combine high-level strategic thinking with hands-on execution
Comfortable working in a lean biotech environment with high accountability
Fluency in English; German is a plus
High-impact leadership role with strategic ownership of late-stage global programs
Science-driven, collaborative biotech culture with flat hierarchies
Flexible, hybrid working model (Europe or US East Coast)