About The Team The Protein Data Bank in Europe (PDBe) is a founding member of the Worldwide Protein Data Bank, the international consortium responsible for maintaining the global archive of experimentally determined macromolecular structures, the Protein Data Bank (PDB). In addition to managing the European PDB data resource, the PDBe team develops a range of tools and services that support structure deposition, data integration, and advanced search capabilities for structural biologists and the wider life science community. PDBe also maintains the PDBe Knowledge Base (PDBe-KB), a community-driven resource launched in 2018 to integrate functional and biophysical annotations for macromolecular structures. The team also co‑develops and operates the AlphaFold Protein Structure Database (AFDB), launched in collaboration with Google DeepMind in July 2021, which provides large‑scale access to AI‑predicted protein structures. The PDBe team consists of an international and interdisciplinary group of scientists, software engineers, and data engineers. PDBe, together with the CS3DB team, forms part of the Molecular and Cellular Structure cluster at EMBL‑EBI. We are seeking an Infrastructure and Production Project Leader to lead the development and operation of the technical infrastructure supporting PDBe services and associated resources, including PDBe‑KB and AFDB. Working Relationships Internal PDBe team members, including software engineers, bioinformaticians, project coordinators, and other project leaders Other EMBL‑EBI teams, including infrastructure, data resources, and platform services External Collaborators across EMBL‑EBI resources, including UniProt Scientific organisations and infrastructure projects such as CCP4, CCPEM, and Science and Technology Facilities Council (STFC) External collaborators from academia, research institutes, and industry Users and stakeholders from the global structural biology community Duties & Responsibilities In This Role You Will Work with the PDBe Team Leader, Coordinator, and senior staff to define and implement the technical strategy for PDBe data infrastructure and services. Lead and manage the Infrastructure and Production sub‑team, including mentoring and supporting team members. Design and operate robust infrastructure supporting the PDBe archive, PDBe‑KB, and AFDB resources. Oversee and continuously improve PDBe’s weekly data release pipelines. Develop scalable mechanisms for data discovery, access, and distribution. Collaborate with other EMBL‑EBI teams, particularly the central IT services, to design and maintain sustainable infrastructure solutions. Act as a technical mentor within the team, fostering best practices in infrastructure engineering, reliability, and maintainability. Monitor emerging technologies and evaluate their potential application to PDBe services. Requirements Master’s degree in Computer Science, Software Engineering, Bioinformatics, Data Engineering, or a related field. Equivalent professional experience in infrastructure engineering and technical leadership will also be considered. A PhD is not essential but domain knowledge in structural biology or bioinformatics is desirable. 6+ years designing and operating large‑scale data infrastructure in production environments. Experience leading and mentoring infrastructure or software engineering teams. Proven track record of delivering reliable and scalable data services. Experience defining and implementing technical roadmaps aligned with organisational strategy. Experience working within scientific or research data environments is desirable. Technical Skills Strong programming skills, particularly in Python. Experience with large‑scale data processing and data integration workflows. Development and operation of RESTful APIs. Experience with relational and/or NoSQL databases. Experience with cloud platforms (e.g., AWS, GCP, Azure). Experience with containerisation and orchestration technologies (Docker, Kubernetes). Experience with Infrastructure‑as‑Code tools (e.g., Terraform). Familiarity with CI/CD pipelines and production monitoring/observability tools. Understanding of cloud security, identity and access management, high availability, and disaster recovery practices. Soft Skills Strong leadership and mentoring capabilities. Excellent communication and collaboration skills. Ability to work effectively within interdisciplinary and international teams. Professional Skills Demonstrated ability to manage large‑scale bioinformatics or data infrastructure projects. Experience improving data infrastructure and access mechanisms within scientific research environments. Desirable Experience in managing a small team Risk Management Able to manage communication with large international consortium members Hybrid Working Hybrid working options are available: a dedicated desk will be provided, with most team members working two days on‑site and three from home. Flexibility to attend on‑site meetings and events is required. Contract Length & Salary Contract length: 3 years (grant‑based). Salary: Grade 7, monthly starting at £4,206 per month after tax (pension and insurance contributions excluded). Plus generous benefits. Benefits Financial incentives: Monthly family, child and non‑resident allowances; annual salary review; pension scheme; death benefit; long‑term care; accident‑at‑work and unemployment insurances. Flexible working arrangements – including hybrid working patterns. Private medical insurance for you and your immediate family. Generous time off: 30 days annual leave plus public holidays. Relocation package including installation grant (if required). Campus life: Free shuttle bus, on‑site library, subsidised gym and cafeteria, casual dress code, extensive sports and social club activities. Family benefits: On‑site nursery, 10 days of child sick leave, generous parental leave, holiday clubs on campus and monthly family and child allowances. Benefits for non‑UK residents: Visa exemption, education grant for private schooling, financial support to travel back to your home country every second year and a monthly non‑resident allowance. Additional Information International applicants: We recruit internationally and successful candidates are offered visa exemptions. For further information, see the International Applicants page. EMBL is a signatory of DORA. Find out how we apply DORA principles to our recruitment and performance assessment processes. Diversity and inclusion: We encourage applications from candidates of all genders, identities, nationalities and any other diverse backgrounds. How to apply: Submit a cover letter and CV through our online system. Applications will close at 23:59 CET on the date shown below. We aim to provide a response within two weeks after the closing date. Closing Date 19/04/2026 #J-18808-Ljbffr