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Master's thesis - nanocarrier development for immune cell targeting (f/m/x)

Helmholtz Association of German Research Centres
Inserat online seit: 24 März
Beschreibung

Area of research:

Diploma & Master Thesis

Job description: Master's Thesis – Nanocarrier Development for Immune Cell Targeting (f/m/x)

102909

Part time
20 hrs./week

Neuherberg near Munich

Partial Home Office possible

At Helmholtz Munich, we develop groundbreaking solutions for a healthier society in a rapidly changing world. We believe that diverse perspectives drive innovation. Through strong partnerships, we accelerate the transfer of new ideas from the lab to real-life applications, improving lives.

At the

Institute for Intelligent Biotechnologies (iBIO)

our major goal is to accelerate biomedical research by developing and combining enabling technologies. Our major research fields are AI-based organ mapping, Tissue engineering and Precision medicine in cancer treatments. Sophisticated technologies such as 3D tissue imaging, molecular profiling are combined with AI tools to decode the complexity of tissues and shed light into cancer biology. Our interdisciplinary team — comprising biologists, engineers, computer scientists, and medical researchers — develops next-generation computational models to interpret complex biomedical data across multiple scales. Our innovations in tissue clearing, 3D microscopy, and AI-driven pathology have been featured in leading journals (Nature Methods, Nature Neuroscience, Cell, Nature Biotechnology) and major media (The New York Times, Wall Street Journal, Süddeutsche Zeitung).

We are seeking a motivated Master's student (f/m/x) with a background in biochemistry, bioengineering, or a related field. The thesis project focuses on the development of lipid nanoparticle (LNP) libraries designed to achieve targeted delivery to immune cell populations.

Your tasks
* Design and evaluation of targeting ligands (e.g., peptides)
* LNP formulation and ligand conjugation
* Physicochemical characterization of nanocarriers
* Library screening using barcoding approaches
* Performance analysis in tissue-cleared mice using light-sheet microscopy
* Quantitative assessment of immune organ and cell-type targeting
Your profile
* Enrolled Master's student in Bioengineering, Biochemistry, Biomedical Sciences, or related discipline
* Solid laboratory experience is required
* Interest in nanotechnology and drug delivery
* Structured, independent working style with ability to work collaboratively in an interdisciplinary team

Desirable qualifications

* Experience with peptide design or in silico tools is a plus
* Experience in primer design, PCR, sequencing is a plus

This position has a fixed term, depending on the requirements of your study program.

Managing Director Mike Frieser: „We believe that diversity is the key to groundbreaking research and innovative solutions. Our flexible working models and remote options create a supportive environment for balancing work and family life. For us, contributing to a healthier society in such an inspiring workplace is truly meaningful.“

Get to know us

Interested in applying?

If you have any questions, feel free to contact Stefanie Reitinger, stefanie.reitinger@helmholtz-munich.de, who will be happy to help.

Our recruiting is decentralized - your application will be reviewed directly by the specialist department in which you could work in the future.

More information about our application process

Please send your application only via our online application tool and with the following documents:

* Cover letter
* CV
* Degrees/Diplomas/Certificates
* Contact details for at least two referees

If you have obtained a university degree abroad, we will require further documents from you regarding the comparability of your degree by the time you start work at the latest.

Please request the Statement of Comparability for Foreign Higher Education Qualifications as early as possible.

We are committed to promoting a culture of diversity and welcome applications from talented people regardless of gender, cultural background, nationality, ethnicity, sexual identity, physical abilities, religion or age. Qualified applicants with physical disabilities will be given preference.

Learn more about diversity at Helmholtz Munich

Our commitment

Helmholtz Munich
Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH)
Institute for Intelligent Biotechnologies
Ingolstädter Landstraße 1
85764 Neuherberg

This research center is part of the Helmholtz Association of German Research Centers. With more than 42,000 employees and an annual budget of over € 5 billion, the Helmholtz Association is Germany's largest scientific organisation.


Company

The Helmholtz Association contributes to solving major challenges to assure the future of our society. With more than 47.500 people on staff in 18 national Research Centers and an annual budget of more than 6 billion euros, the Helmholtz Association is Germany’s largest scientific organization. The name Helmholtz stands for concerted research, in which networks form the key principle behind inquiring thought and action.

The profile of the Helmholtz Association

The Helmholtz Association performs cutting-edge research which contributes substantially to solving the grand challenges of science, society and industry. To succeed in meeting these responsibilities, Helmholtz concentrates its work in six research fields: Energy, Earth and Environment, Health, Information, Matter, as well as Aeronautics, Space and Transport. Within each of these fields, research programs are developed by our scientists and regularly evaluated by renowned international experts. Their evaluation forms the basis for the program-oriented funding that is allocated to Helmholtz research. Within the six research fields, Helmholtz scientists cooperate with each other and with external partners – working across disciplinary, organizational and national borders.

Moreover, Helmholtz specializes in large-scale research infrastructures – from accelerator facilities, earth observation satellites, research ships to supercomputers. They form the basis for scientific advances in tackling global societal challenges. Managing national research infrastructure is part of the Helmholtz Association's mission.

Promoting young academics

Helmholtz scientists, a high-performance infrastructure and modern and efficient research management are the ingredients to the Helmholtz Association‘s success and global impact.
Promoting young researchers is a major priority for the Helmholtz Association. Its qualification schemes for young researchers are geared mainly towards PhD students, postdocs and young managers. The Helmholtz Association has set high standards for its talent management. Its strategy begins with targeted recruitment of highly qualified staff at all levels, followed by comprehensive support aimed at further developing their potential. Ensuring equal opportunities is an essential element in all talent management activities undertaken by the Helmholtz Association.

The Helmholtz Graduate Schools and Research Schools at almost all Helmholtz Centers provide doctoral students with the general and specific skills and training they need, as well as ample opportunity to network. The period following a doctorate is decisive in determining the direction and success of a scientific career. For this reason, we established Career Development Centers for postdoctoral researchers in the Helmholtz Centers. This equips young researchers with the skills they need to go on to head a Helmholtz Investigator Group, for example. As an Investigator Group leader, junior scientists can independently set up their own group to conduct research in their specialist field and acquire management skills.

Within its talent management strategy, the Helmholtz Association pays special attention to the increased recruitment of talented female scientists both from Germany and abroad. To this end, there are currently two funding programs supporting this policy: and Helmholtz Distinguished Professorship – Funding for the recruitment of leading international female scientists (W3) .

The increasing complexity of the content, structures and framework conditions of scientific work today requires researchers to organize their projects, their employees and, of course, themselves in a highly professional and effective way. In response to these demands, we have set up the Helmholtz Leadership Academy to provide leaders in science with professional management training. Furthermore, the Helmholtz network provides a platform for the alumni of the Helmholtz Leadership Academy to come together and share their experiences of leadership, career development and lifelong learning.

All of this combined makes the 18 Research Centers of the Helmholtz Association a highly attractive environment for talented researchers from all over the world.

Company info

Telephone
0049-30-206329-0
Location
Anna-Louisa-Karsch-Str. 2
Berlin
Berlin
10178
Germany

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