Clinic and Polyclinic for Pediatric and Adolescent Medicine Project focus: Analysis of the transgenerational effect of maternal and early childhood obesity on the health of offspring.
Furthermore
Identification of cellular as well as intercellular networks of early aging processes after perinatal stress
Characterization of pulmonary phenotype using lung function measurements, quantitative lung morphometry and immunohistochemical and immunofluorescence-based analyses
Flow cytometry analysis
Independently perform physiological examinations
Close scientific collaboration in an international team under supervision of the group leader and the PostDocs
Analysis of collected data including storage and statistical analysis
Writing of scientific abstracts/manuscripts and publications in peer-reviewed journals
Participation in scientific congresses, as well as presentation of the work (poster presentations, lectures)
Planning, management and coordination of animal experimental, cell biological as well as bioinformatic studies
PhD-Requirements:
Degree (M.Sc. or equivalent) in life sciences (e.g. medicine, biology or a comparable qualification)
Strong interest in lung development and applied lung biology
Excellent knowledge of English is mandatory, as the laboratory language is English
The applicant should have an extraordinary degree of independence and initiative and be able to represent the Institute appropriately in public relations
He/she should be a team player, creative, enthusiastic and passionate about biomedicine
Knowledge of data storage and analysis
Expertise in the following methods:
Knowledge of experimental models of cardiopulmonary diseases, such as animal models of as chronic hypoxia/hyperoxia and high-fat diet models
Experience with cell biology methods
Immunohistochemistry and immunofluorescence
Carrying out cell culture experiments.
Isolation and cultivation of primary cells
Quantitative histomorphometry of the lung including organ fixation and organ harvesting
FACS-analyses
Experience in animal physiology and cell biology work
Experience in animal handling and experimental design using genetic modified mice (e.g. Cre-Lox); comprehensive pathophysiological knowledge. Applicants with experience in handling laboratory animals and genetically modified mice including anesthesia and injection techniques are preferred
A varied job in a highly interesting and challenging research topic
A fair working environment with appreciative cooperation
Possibility to develop side projects according to personal interests
Internal and external training opportunities
Flexible working time models to support family life
Occupational health management offers