About Numaferm
Numaferm is a fast-growing biotech company, pioneering innovation in peptide and protein production through recombinant expression technologies. With a strong scientific foundation and a commercial mindset, we are driving impactful solutions for clients across pharma, biotech, and industrial sectors. At Numaferm, you’ll have the opportunity to grow with us and shape the future of molecular biology.
Job Title: Scientist / PostDoc - Molecular Biology, Library Design & Construction (m/f/d)
Location: Düsseldorf, Germany
Company: Numaferm GmbH
Job Type: Fixed-Term (1 Year), Full-Time
Start Date: As soon as possible
We are looking for a motivated and creative Scientist or Postdoctoral Researcher to join our Molecular Biology & Library Design team. You will play a key role in the design, construction, and screening of DNA libraries and molecular toolsets. You will also contribute to innovative internal R&D and support customer-driven projects.
This role is an excellent opportunity to work on cutting-edge technologies at the interface of synthetic biology, molecular design, and bioinformatics. The position is lab-based, including data analysis, concept development, and direct project communication with clients.
Key Responsibilities
Laboratory & Technical Work
Design and construct gene libraries using advanced cloning techniques such as Gibson Assembly, BSA Cloning, Gateway Cloning, and others
Apply bioinformatic tools to design gene constructs, optimize sequences, and analyze data
Perform molecular biology workflows including DNA/RNA manipulation, PCR, sequencing, and recombinant protein expression
Support both internal research and external client projects with high scientific and technical standards
Client Interaction & Communication
Serve as a scientific point of contact during customer project execution
Present designs, timelines, and results to clients in a professional and clear manner
Contribute to proposals, reports, and presentations
Conceptual & Strategic Development
Develop and implement innovative molecular biology workflows
Evaluate new technologies for molecular and protein engineering
PhD in Molecular Biology, Biotechnology, Synthetic Biology, or a related field
Proven hands-on experience in molecular cloning and construct design
Familiarity with gene library design and generation
Experience with bioinformatic tools for DNA/RNA sequence analysis and optimization
Strong communication skills and ability to work collaboratively
Fluent in English and German (written and spoken)
Additional Desired Qualifications
Experience with the amber stop codon strategy and genetic code expansion
Expertise in homologous recombination for gene knock-in/knock-out
Expertise with E. coli cell-free expression systems
Practical experience with CRISPR/Cas9 genome editing
Hands-on knowledge of E. coli small- to mid-scale fermentation
Familiarity with recombinant protein expression in microbial systems
Experience with bioinformatic tools for protein design and optimization, including rational design or AI-driven approaches (e.g., structure prediction, stability engineering, in silico mutagenesis)
A one-year employment contract with a clear potential for extension
A dynamic, collaborative work environment in a high-growth biotech company
Flat hierarchies, flexibility, and the chance to contribute your own ideas
Meaningful projects with real-world application in medicine and biotech
The opportunity to grow with the company and take on new responsibilities